Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932356 | 0.88 | TSHR (0.46) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL27914160 | 0.88 | TNF (0.43) | LMNAALDH1A1HTTTNFL3MBTL1 | |
| SCHEMBL692174 | 0.87 | LMNA (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL12268259 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL27462122 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8771122 | 0.84 | SLC6A3 (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL5862004 | 0.84 | LMNA (0.47) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL29697542 | 0.83 | L3MBTL1 (0.47) | LMNASLC6A3L3MBTL1SLC6A4RAB9A | |
| SCHEMBL8770926 | 0.83 | L3MBTL1 (0.47) | LMNASLC6A3L3MBTL1SLC6A4RAB9A | |
| SCHEMBL8770867 | 0.83 | ALDH1A1 (0.42) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261176-A | 1, 4-oxazepane derivatives | TAKAEDA CHEMICAL IND LTD | 2013-08-21 | — | — | CN | disclosed |
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |