Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927213 | 0.72 | L3MBTL1 (0.65) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL112782 | 0.71 | HPGD (0.59) | LMNAMMP13SCN9AMAPTHPGD | |
| SCHEMBL6923722 | 0.66 | NAT1 (0.50) | DAOLMNASCN9AMAPTHPGD | |
| SCHEMBL8631022 | 0.66 | RAB9A (0.67) | LMNAMAPTHPGDTSHRMEN1 | |
| SCHEMBL6865826 | 0.64 | DAO (0.49) | DAOLMNASCN9AMAPTPOLB | |
| SCHEMBL14027247 | 0.64 | DAO (0.55) | DAOLMNASCN9AMAPTPOLB | |
| SCHEMBL9692985 | 0.64 | RAB9A (0.60) | DAOLMNAHPGDMEN1KMT2A | |
| SCHEMBL8659490 | 0.64 | OPRL1 (0.49) | DAOLMNA | |
| SCHEMBL16815776 | 0.63 | HCAR2 (0.37) | HPGDTSHR | |
| SCHEMBL6929765 | 0.63 | CYP3A4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |