Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.34 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930500 | 0.85 | ALDH1A1 (0.35) | ACHETLR7ACP1 | |
| SCHEMBL6929019 | 0.84 | NPY1R (0.43) | HTR6TLR7CYP1A2ACP1 | |
| SCHEMBL6926471 | 0.81 | ACHE (0.45) | HTR7HTR6HTR2AACHETLR7 | |
| SCHEMBL27569952 | 0.73 | ACHE (0.36) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL6840151 | 0.73 | HTR4 (0.41) | HTR6TLR7CYP1A2GLAACP1 | |
| SCHEMBL6922241 | 0.73 | NPY1R (0.40) | HTR6ACP1 | |
| SCHEMBL6926668 | 0.72 | IDO1 (0.40) | ACHETLR7ACP1TLR8 | |
| SCHEMBL6929042 | 0.72 | NPY1R (0.40) | HTR6ACP1 | |
| SCHEMBL6927830 | 0.71 | ADRB2 (0.40) | HTR6 | |
| SCHEMBL6924891 | 0.69 | DYRK3 (0.40) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |