Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | ACP1 | P24666 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927830 | 0.90 | ADRB2 (0.40) | NPY1RPIM1KCNH2PIM3PIM2 | |
| SCHEMBL6929019 | 0.88 | NPY1R (0.43) | NPY1RSLC6A4ACP1MAOBHTR6 | |
| SCHEMBL6924891 | 0.88 | DYRK3 (0.40) | NPY1RACP1CTSS | |
| SCHEMBL6930321 | 0.83 | NPY1R (0.43) | NPY1RSLC6A4PIM1ACP1MAOB | |
| SCHEMBL6929031 | 0.81 | SLC6A4 (0.40) | NPY1RSLC6A4PIM1ACP1MAOB | |
| SCHEMBL6837746 | 0.78 | NPY1R (0.41) | NPY1RSLC6A4PIM1ACP1 | |
| SCHEMBL6840151 | 0.76 | HTR4 (0.41) | NPY1RSLC6A4ACP1MAOBHTR6 | |
| SCHEMBL6927586 | 0.74 | NPY1R (0.39) | NPY1RPIM1ACP1PIM3PIM2 | |
| SCHEMBL6929042 | 0.73 | NPY1R (0.40) | NPY1RACP1MAOBHTR6 | |
| SCHEMBL6926314 | 0.73 | HTR7 (0.34) | ACP1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |