Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | HTR6 | P50406 | 6/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 5/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840151 | 0.88 | HTR4 (0.41) | NPY1RHTR4MAOBHTR6TLR7 | |
| SCHEMBL6922241 | 0.88 | NPY1R (0.40) | NPY1RMAOBHTR6ACP1SLC6A4 | |
| SCHEMBL6927830 | 0.86 | ADRB2 (0.40) | NPY1RHTR4HTR6ADRB2 | |
| SCHEMBL6929042 | 0.84 | NPY1R (0.40) | NPY1RHTR4MAOBHTR6ACP1 | |
| SCHEMBL6925914 | 0.84 | NPY1R (0.44) | NPY1RHTR4MAOBHTR6ACP1 | |
| SCHEMBL6926314 | 0.84 | HTR7 (0.34) | HTR6TLR7ACP1CYP1A2 | |
| SCHEMBL6924891 | 0.84 | DYRK3 (0.40) | NPY1RACP1 | |
| Hydrochloric Acid SCHEMBL6923145 | 0.83 | NPY1R (0.43) | NPY1RHTR4MAOBHTR6ACP1 | |
| SCHEMBL6929551 | 0.82 | PDE6D (0.41) | NPY1RHTR4MAOBHTR6ACP1 | |
| SCHEMBL6833769 | 0.82 | HTR4 (0.39) | NPY1RHTR4TLR7ACP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |