SCHEMBL6928494

SCHEMBL6928494

CCCCC(CC)COC(C=O)Cc1cc(-c2nc3cc(Cl)ccc3s2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SENP7 Q9BQF6 2/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
PPARA Q07869 8/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
AGPAT2 O15120 4/20 0.34
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.32
GUSB P08236 1/20 0.30
ATP4A P20648 1/20 0.30
ATP4B P51164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928491 0.83 ALDH1A1 (0.42) SENP7CASP3SENP8SENP6PPARA
SCHEMBL7226047 0.81 ALDH1A1 (0.33) ALDH1A1MAPK1
SCHEMBL76645 0.79 ALDH1A1 (0.34) ALDH1A1MAPK1
SCHEMBL7647075 0.77 ALDH1A1 (0.31) ALDH1A1MAPK1
SCHEMBL30672844 0.75 SENP7 (0.41) SENP7CASP3SENP8SENP6PPARA
SCHEMBL29269889 0.75 SENP7 (0.41) SENP7CASP3SENP8SENP6PPARA
SCHEMBL295015 0.73 CA2 (0.34) GAAALDH1A1
SCHEMBL7931248 0.72 L3MBTL1 (0.42) GAAALDH1A1MAPK1
SCHEMBL6050509 0.72 SENP7 (0.44) SENP7CASP3SENP8SENP6PPARA
SCHEMBL7642933 0.70 AGPAT2 (0.47) SENP7CASP3SENP8SENP6PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465943-A2 FLAME RETARDANT CONPOSITIONS Ciba SC Holding AG (CH) 2004-10-13 EP disclosed
WO-2003050175-A2 FLAME RETARDANT CONPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-19 WO disclosed
EP-1232209-A1 DIMERIC LIGHT STABILIZERS FOR POLYOLEFINS AND POLYOLEFIN COPOLYMERS Ciba SC Holding AG (CH) 2002-08-21 EP disclosed
WO-2001040367-A1 DIMERIC LIGHT STABILIZERS FOR POLYOLEFINS AND POLYOLEFIN COPOLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-06-07 WO disclosed
WO-1998054174-A1 BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-12-03 WO disclosed