Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | GBA1 | P04062 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552337 | 0.80 | ACHE (0.48) | HTR2ALMNAACHEPOLB | |
| SCHEMBL6925393 | 0.79 | ACHE (0.46) | HTR2ALMNAACHEPOLB | |
| SCHEMBL6926471 | 0.78 | ACHE (0.45) | HTR6HTR2AHTR7LMNAACHE | |
| SCHEMBL6925999 | 0.78 | ACHE (0.43) | HTR6HTR2ALMNAACHEPOLB | |
| Hydrochloric Acid SCHEMBL6925023 | 0.76 | HTR4 (0.48) | HTR6HTR2AHTR7HTR1AACHE | |
| Trifluoroacetic Acid SCHEMBL6928326 | 0.75 | NR3C1 (0.45) | HTR6HTR2ALMNAACHEPOLB | |
| SCHEMBL6927078 | 0.75 | KDM4E (0.45) | KDM4EACHEPKM | |
| SCHEMBL6928736 | 0.72 | ACP1 (0.42) | HTR6HTR2AHTR7HTR1ADRD2 | |
| SCHEMBL10728919 | 0.72 | YTHDC1 (0.46) | KMT2AHTR2AALDH1A1KDM4ELMNA | |
| SCHEMBL9602030 | 0.69 | TLR7 (0.47) | KMT2AHTR2ASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |