Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6923561

O=C(O)C(F)(F)F.c1ccc(Oc2nc3ccccc3c3c2ncn3CCC2CCNCC2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 1/20 0.41
NR3C1 P04150 1/20 0.39
ACHE P22303 1/20 0.36
NPY1R P25929 2/20 0.36
TLR7 Q9NYK1 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RAB9A P51151 1/20 0.34
HTR1A P08908 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CHRM3 P20309 1/20 0.34
TACR3 P29371 1/20 0.33
KCNH2 Q12809 1/20 0.33
AVPR2 P30518 1/20 0.33
AVPR1A P37288 1/20 0.33
ITGB3 P05106 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6928326 0.85 NR3C1 (0.45) HTR4NR3C1ACHENPY1RTLR7
SCHEMBL6929721 0.84 ACHE (0.43) ACHETLR7LMNATSHRHTT
SCHEMBL6926916 0.79 CSF1R (0.44)
SCHEMBL6838687 0.79 HTR4 (0.41) HTR4NR3C1ACHENPY1RTLR7
SCHEMBL6928736 0.79 ACP1 (0.42) HTR4ACHETLR7LMNATSHR
SCHEMBL6096772 0.77 TLR7 (0.56) HTR4ACHENPY1RTLR7LMNA
SCHEMBL6925999 0.77 ACHE (0.43) HTR4NR3C1ACHENPY1RTLR7
Hydrochloric Acid SCHEMBL6929408 0.76 TLR7 (0.55) HTR4ACHENPY1RTLR7LMNA
SCHEMBL6702926 0.75 TLR7 (0.44) TLR7LMNAHTTRAB9AKCNH2
SCHEMBL1140794 0.70 LMNA (0.49) HTR4NR3C1ACHENPY1RLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed