Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 5/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098179 | 0.80 | ALDH1A1 (0.38) | LMNAGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7159601 | 0.80 | ACHE (0.38) | LMNAGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7159560 | 0.80 | ROCK2 (0.38) | LMNAGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL5689270 | 0.79 | CTSA (0.44) | SMN1; SMN2AAK1CTSAIDO1ACHE | |
| SCHEMBL7161306 | 0.77 | ACHE (0.38) | LMNAGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7228596 | 0.77 | ACHE (0.38) | LMNAGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL11051393 | 0.74 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2KMT2AIDO1ACHE | |
| SCHEMBL5752958 | 0.74 | SRD5A1 (0.44) | GAASMN1; SMN2KMT2A | |
| SCHEMBL1906698 | 0.73 | KDM4E (0.42) | LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7247069 | 0.73 | ADRB3 (0.43) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |