Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051393 | 0.84 | SMN1; SMN2 (0.45) | IDO1SMN1; SMN2ACHE | |
| SCHEMBL6929116 | 0.79 | CASR (0.39) | CTSAAAK1KITIDO1SMN1; SMN2 | |
| SCHEMBL6266844 | 0.71 | CYP2D6 (0.46) | CTSADHFR | |
| SCHEMBL7159560 | 0.70 | ROCK2 (0.38) | SMN1; SMN2ACHE | |
| SCHEMBL7159601 | 0.70 | ACHE (0.38) | SMN1; SMN2ACHE | |
| SCHEMBL7098179 | 0.70 | ALDH1A1 (0.38) | KITSMN1; SMN2ACHE | |
| SCHEMBL5688780 | 0.70 | RAB9A (0.47) | CTSAAAK1KIT | |
| SCHEMBL21376221 | 0.70 | DHFR (0.48) | CTSADHFR | |
| SCHEMBL5688342 | 0.69 | CYP17A1 (0.44) | CTSAAAK1KITIDO1 | |
| SCHEMBL11045849 | 0.69 | TSHR (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |