Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 5/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424202 | 0.76 | KDM4E (0.45) | WEE1PARP1CHEK1KDM4EALDH1A1 | |
| Water SCHEMBL10733874 | 0.75 | KDM4E (0.44) | WEE1PARP1CHEK1KDM4EALDH1A1 | |
| SCHEMBL28597691 | 0.72 | ELANE (0.40) | PARP1CHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL10911536 | 0.72 | GSK3B (0.41) | WEE1PARP1PPOXCHEK1KDM4E | |
| SCHEMBL31195685 | 0.71 | PARP1 (0.35) | WEE1PARP1PPOXCHEK1GSK3B | |
| SCHEMBL10119220 | 0.70 | PPOX (0.39) | PPOXCHEK1KDM4EALDH1A1HPGD | |
| SCHEMBL1864583 | 0.70 | ELANE (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11212344 | 0.70 | CDK4 (0.35) | WEE1PARP1PPOXKDM4EALDH1A1 | |
| SCHEMBL28709694 | 0.69 | GRIA1 (0.38) | WEE1PARP1PPOXCHEK1HPGD | |
| SCHEMBL19667897 | 0.69 | CYP4F2 (0.40) | WEE1PARP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518450-B2 | Adrenergic blocking agent | NATIONAL SCIENCE COUNCIL (TW) | 2003-02-11 | — | — | US | disclosed |
| US-20010056211-A1 | Guaiacoxypropanolamines with alpha/beta adrenergic blocking activity | NATIONAL SCIENCE COUNCIL (TW) | 2001-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056211-A1 | Guaiacoxypropanolamines with alpha/beta adrenergic blocking activity | ADRB1, ADRA1A, ADRA1B | WEE1 4645/4885PARP1 3080/4885PPOX 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.