Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.45 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619904 | 0.90 | REN (0.46) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL7473368 | 0.89 | CTSK (0.52) | CTSSCTSBCTSKCTSLCAPN1 | |
| SCHEMBL7819471 | 0.86 | REN (0.47) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL6620241 | 0.85 | CTSS (0.42) | CTSSCTSBCTSKCTSLBACE1 | |
| SCHEMBL6927161 | 0.85 | CTSS (0.42) | CTSSCTSBCTSKCTSLBACE1 | |
| SCHEMBL7470442 | 0.84 | CTSL (0.47) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6623377 | 0.83 | CTSL (0.47) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6620163 | 0.82 | HSPA5 (0.49) | CTSSCTSBCTSKCTSL | |
| Trifluoroacetic Acid SCHEMBL7611852 | 0.81 | CTSL (0.45) | CTSSCTSBCTSKCTSLBACE1 | |
| SCHEMBL7819470 | 0.79 | CTSL (0.38) | CTSSCTSBCTSKCTSLBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |