Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930495 | 0.76 | CHRM2 (0.44) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL11772501 | 0.66 | ADRA2A (0.38) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL11771917 | 0.65 | CHRM2 (0.37) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL11772425 | 0.65 | CHRM2 (0.37) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL3284155 | 0.64 | MAOA (0.55) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL11769706 | 0.64 | ADRA2A (0.37) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL10728179 | 0.63 | DRD1 (0.86) | DRD1DRD3CHRM2HTR1AADRA2A | |
| Setiptiline SCHEMBL211362 | 0.62 | DRD1 (1.00) | DRD1DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL202264 | 0.61 | TSHR (0.44) | DRD1DRD3CHRM2HTR1AADRA2A | |
| Lithium SCHEMBL7545662 | 0.60 | SIGMAR1 (0.43) | DRD1DRD3CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670680-A | Method for producing octahydrofluorenyl metal complexes | THE DOW CHEMICAL COMPANY (US) | 1997-09-23 | — | — | US | claimed |