SCHEMBL6931503

SCHEMBL6931503

CC(C)(C)CC(C)(C)c1cccc(N(c2ccccc2)C(C)(C)CC(C)(C)C)c1C(C)(C)CC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3450294 0.88 ESR1 (0.31)
SCHEMBL252529 0.80 ALDH1A1 (0.33)
SCHEMBL871746 0.76 SIGMAR1 (0.44)
SCHEMBL44715 0.76 MEN1 (0.38)
SCHEMBL27828659 0.71 CYP3A4 (0.35)
SCHEMBL11787355 0.69 SIRT2 (0.39)
SCHEMBL28890805 0.68 MEN1 (0.31)
SCHEMBL9813822 0.68 HTR6 (0.39)
SCHEMBL7597677 0.66 SHBG (0.42)
SCHEMBL29945080 0.66 MAPT (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023377-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2003-12-03 EP claimed
US-6348514-B1 ISOCYANATE REACTIVE COMPOSITION WITH STABILIZER OF METHYL 3-(4-HYDROXY-3,5-DI-TERT-BUTYLPHENYL)PROPIONATE UNIROYAL CHEMICAL COMPANY, INC. 2002-02-19 US claimed
EP-1023377-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 2000-08-02 EP claimed
WO-1999016821-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP claimed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
US-5571453-A PHOTOSTABILITY USING REACTION PRODUCT OF DIPHENYLAMINE, ISOBUTYLENE AND DIISOBUTYLENE AND STERICALLY HINDERED PHENOL AND TRIHYDROCARBYL PHOSPHITE UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-05 US disclosed
WO-1996012760-A2 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-05-02 WO disclosed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP disclosed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO disclosed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US disclosed
EP-0399142-B1 Stabilizer compositions for polyols and polyurethane foam VANDERBILT CO R T (US) 1994-01-26 EP disclosed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US disclosed
EP-0556612-A1 Synergistic stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1993-08-25 EP disclosed
US-5156762-A 2,6-Di-tert-butyl-4-sec-butylphenol, phenothiazine or alkyl-substitued derivative, and reaction product of styrene, diisobutylene and diphenylamine R. T. VANDERBILT COMPANY, INC. (US) 1992-10-20 US disclosed
US-5143943-A 2,6-di-tert-butyl-4-sec-butylphenol; reaction product of styrene, diphenylamine, and diisobutylene; and phenothiazine compound; discoloration inhibition R. T. VANDERBILT COMPANY, INC. (US) 1992-09-01 US disclosed
EP-0399142-A2 Stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, INC. (US) 1990-11-28 EP disclosed
US-4933374-A 2,6-DI-TERT-BUTYL-4-SEC-BUTYLPHENOL, REACTION PRODUCT OF DIISOBUTYLENE, STYRENE AND DIPHENYLAMINE R. T. VANDERBILT COMPANY, INC. (US) 1990-06-12 US disclosed