Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44715 | 0.76 | MEN1 (0.38) | KMT2ASMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL3450294 | 0.73 | ESR1 (0.31) | KMT2ASMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL871746 | 0.73 | SIGMAR1 (0.44) | KMT2AMEN1CYP2C19ALDH1A1MAPT | |
| SCHEMBL2762268 | 0.72 | MAPT (0.46) | SIRT2SMN1; SMN2CYP3A4CYP2C19BCAT2 | |
| SCHEMBL7093772 | 0.71 | BCAT2 (0.47) | SIRT2SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7259310 | 0.71 | ALDH1A1 (0.44) | SIRT2KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL4251059 | 0.70 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL10992096 | 0.70 | SIRT1 (0.46) | SIRT2SMN1; SMN2CYP3A4CYP2C19BCAT2 | |
| SCHEMBL28050368 | 0.69 | NPC1 (0.45) | SIRT2KMT2ASMN1; SMN2MEN1BCAT2 | |
| SCHEMBL28051317 | 0.69 | BCAT2 (0.42) | SIRT2SMN1; SMN2CYP3A4CYP2C19BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984337-A | N-1,1,3,3-TETRAMETHYLBUTYL-2-(1-NAPHTHYLAMINO)BENZAMIDE | MOBIL OIL CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |