Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.37 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199976 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL8885912 | 0.77 | CA1 (0.40) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL11294282 | 0.77 | MTNR1A (0.64) | MTNR1AMTNR1BTAOK1TAOK3 | |
| SCHEMBL8887633 | 0.76 | HTR1D (0.57) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL7073835 | 0.75 | DRD2 (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL7073836 | 0.75 | DRD2 (0.54) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8686894 | 0.74 | DRD2 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL8884861 | 0.74 | GAA (0.43) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL6561215 | 0.69 | GRM7 (0.60) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL11298161 | 0.69 | MTNR1A (0.54) | MTNR1AMTNR1BTAOK1TAOK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768307-B1 | Heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-11-26 | — | — | EP | disclosed |
| EP-0768307-A1 | Heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-04-16 | — | — | EP | disclosed |