SCHEMBL6933019

SCHEMBL6933019

ClC(Cl)(Cl)Sc1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
MAOA P21397 4/20 0.37
MAOB P27338 4/20 0.37
HAO1 Q9UJM8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 5/20 0.33
ALOX15 P16050 2/20 0.33
MAPK1 P28482 2/20 0.33
TRPA1 O75762 1/20 0.33
FBP1 P09467 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779804 0.86 KDM4E (0.38) ALDH1A1TDP1KDM4E
SCHEMBL25118403 0.77 KDM4E (0.35) CYP2A6MAOAMAOBSMN1; SMN2ALDH1A1
SCHEMBL7938138 0.74 ALDH1A1 (0.36) MAOAMAOBSMN1; SMN2ALDH1A1FBP1
SCHEMBL7940598 0.74 NR1H2 (0.50) ALDH1A1ALOX15TDP1KDM4E
SCHEMBL381447 0.74 ALDH1A1 (0.58) CYP2A6MAOAMAOBSMN1; SMN2ALDH1A1
SCHEMBL4411163 0.74 SLC6A4 (0.45) CYP2A6MAOAMAOBHAO1SMN1; SMN2
SCHEMBL8486201 0.74 IDO1 (0.39) ALDH1A1TDP1KDM4E
SCHEMBL1260200 0.70 CYP2A6 (0.38) CYP2A6MAOAMAOBHAO1SMN1; SMN2
SCHEMBL21299983 0.70 CYP2A6 (0.38) CYP2A6MAOAMAOBHAO1SMN1; SMN2
SCHEMBL18967981 0.70 CYP2A6 (0.38) CYP2A6MAOAMAOBHAO1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181270-B2 Method of making sulfide compounds UNIVERSAL DISPLAY CORPORATION (US) 2015-11-10 US disclosed
US-9181270-B2 Method of making sulfide compounds UNIVERSAL DISPLAY CORPORATION (US) 2015-11-10 US disclosed
US-9181270-B2 Method of making sulfide compounds UNIVERSAL DISPLAY CORPORATION (US) 2015-11-10 US disclosed
US-20150246928-A1 METHOD OF MAKING SULFIDE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-20150246928-A1 METHOD OF MAKING SULFIDE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-20150246928-A1 METHOD OF MAKING SULFIDE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
EP-0742201-B1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS (JP) 2003-02-05 EP disclosed
CN-1076346-C Process for preparing aromatic or heteroaromatic sulfur compounds SUMITOMO SEIKA CHEMICALS (JP) 2001-12-19 CN disclosed
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed
US-5741933-A HYDROLYSIS; OXIDATION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-21 US disclosed
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP disclosed
CN-1139428-A Process for producing aromatic or heteroaromatic sulfur compounds SUMITOMO SEIKA CHEMICALS (JP) 1997-01-01 CN disclosed
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246928-A1 METHOD OF MAKING SULFIDE COMPOUNDS CBS, SCLY, QSOX1 CYP2A6 874/4885MAOA 1646/4885MAOB 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.