Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389462 | 0.76 | AHR (0.45) | MAPTNFE2L2MAOBAHR | |
| SCHEMBL9592335 | 0.74 | TDP1 (0.48) | ALDH1A1NPC1MAPTNFE2L2DHODH | |
| SCHEMBL9664423 | 0.74 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTNFE2L2MAOB | |
| SCHEMBL7011173 | 0.74 | NFE2L2 (0.41) | ALDH1A1NPC1MAPTNFE2L2PTGS1 | |
| SCHEMBL13354684 | 0.72 | NMT1 (0.41) | NPC1PTGS2AHR | |
| SCHEMBL11411053 | 0.70 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTPTGS1PTGS2 | |
| SCHEMBL11411172 | 0.69 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTPTGS1PTGS2 | |
| SCHEMBL9591612 | 0.69 | TDP1 (0.56) | ALDH1A1NPC1MAPTAHR | |
| SCHEMBL867378 | 0.69 | PTGS2 (0.41) | NFE2L2PTGS1PTGS2ALOX5 | |
| SCHEMBL8556572 | 0.69 | PTGS2 (0.41) | NFE2L2PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313426-A2 | SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | Bristol-Myers Squibb Pharma Company (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1313426-A4 | SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2000038618-A2 | SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF Aβ PROTEIN PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |