SCHEMBL6937358

SCHEMBL6937358

CCOC(=O)/C=C/COc1cc(-c2c(Cl)c(C(F)(F)F)n(C)c2Cl)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.36
XPO1 O14980 1/20 0.33
PPOX P50336 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937364 1.00 RAB9A (0.36) RAB9AXPO1PPOXRECQLSMN1; SMN2
SCHEMBL6935585 0.84 PPOX (0.46) PPOXALDH1A1MAPTMRGPRX4LMNA
SCHEMBL6934937 0.80 LMNA (0.33) PPOXLMNA
SCHEMBL6937330 0.80 PTGDR2 (0.39) ALDH1A1
SCHEMBL7693094 0.80 LMNA (0.33) PPOXLMNA
SCHEMBL6937105 0.79 KDM4E (0.36) PPOXSMN1; SMN2ALDH1A1LMNA
SCHEMBL6938757 0.78 CNR2 (0.32) ALDH1A1MAPT
SCHEMBL6935030 0.78 PTGDR2 (0.34) PPOXMRGPRX4LMNA
SCHEMBL7074077 0.77 LMNA (0.33) PPOXLMNA
SCHEMBL6937559 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP disclosed
US-6391827-B1 CONTROLLING WEEDS ISAGRO RICERCA S.R.L. (IT) 2002-05-21 US disclosed
EP-1061072-A1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA S.r.l. (IT) 2000-12-20 EP disclosed