Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934266 | 0.79 | HTR1A (0.59) | HTR1AALDH1A1MEN1BLMKMT2A | |
| SCHEMBL5915126 | 0.68 | DRD2 (0.51) | HTR1AMAPTHTR2AHTR2CHTR2B | |
| SCHEMBL2429178 | 0.68 | HTR1A (0.51) | HTR1AALDH1A1MEN1BLMKMT2A | |
| SCHEMBL7040218 | 0.67 | HTR1A (0.61) | HTR1AHTR2AHTR2BMEN1BLM | |
| SCHEMBL7734622 | 0.66 | HTR6 (0.39) | MAPTALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL15210114 | 0.66 | PKM (0.40) | MAPTALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL6933895 | 0.65 | HTR1A (0.58) | HTR1AALDH1A1MEN1BLMKMT2A | |
| SCHEMBL9527372 | 0.65 | HTR2C (0.46) | MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL6930437 | 0.65 | HTR1A (0.58) | HTR1AMAPTALDH1A1MEN1BLM | |
| SCHEMBL6930463 | 0.64 | HTR1A (0.51) | HTR1AALDH1A1MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000047-B1 | 1-(N-PHENYLAMINOALKYL)-PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING | RECORDATI CHEM PHARM (CH) | 2003-12-17 | — | — | EP | disclosed |