Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936452 | 0.80 | CES1 (0.30) | — | |
| SCHEMBL26932394 | 0.79 | CA1 (0.35) | ALDH1A1 | |
| SCHEMBL1967431 | 0.79 | PTGS2 (0.32) | — | |
| SCHEMBL691617 | 0.77 | ALDH1A1 (0.35) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL11208396 | 0.72 | — | — | |
| SCHEMBL9236268 | 0.71 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL5509097 | 0.71 | CYP2C9 (0.35) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL6631300 | 0.68 | LMNA (0.33) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6630125 | 0.68 | CYP2D6 (0.32) | TSHR | |
| SCHEMBL8818743 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143022-B1 | CARBOPYRONONE COMPOUNDS USEFUL AS DIAGNOSTIC ADJUVANTS | LIFE TECHNOLOGIES CORP (US) | 2021-12-22 | — | — | EP | claimed |
| US-20210324198-A1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation | 2021-10-21 | — | — | US | claimed |
| EP-3314257-B1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | LIFE TECHNOLOGIES CORP (US) | 2021-06-16 | — | — | EP | claimed |
| EP-3833715-A2 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation (US) | 2021-06-16 | — | — | EP | claimed |
| US-20200408739-A1 | Carbopyronone Compounds Useful as Diagnostic Adjuvants | Life Technologies Corporation | 2020-12-31 | — | — | US | claimed |
| US-10739330-B2 | Carbopyronone compounds useful as diagnostic adjuvants | Life Technologies Corporation (US) | 2020-08-11 | — | — | US | claimed |
| WO-2020033681-A2 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation (US) | 2020-02-13 | — | — | WO | claimed |
| EP-3502693-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation (US) | 2019-06-26 | — | — | EP | claimed |
| US-20180340928-A1 | Carbopyronone Compounds Useful as Diagnostic Adjuvants | Life Technologies Corporation | 2018-11-29 | — | — | US | claimed |
| US-20180196033-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation | 2018-07-12 | — | — | US | claimed |
| US-10018617-B2 | Carbopyronone compounds useful as diagnostic adjuvants | Life Technologies Corporation (US) | 2018-07-10 | — | — | US | claimed |
| EP-3314257-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation (US) | 2018-05-02 | — | — | EP | claimed |
| EP-3143022-A1 | CARBOPYRONONE COMPOUNDS USEFUL AS DIAGNOSTIC ADJUVANTS | Life Technologies Corporation (US) | 2017-03-22 | — | — | EP | claimed |
| US-20170045496-A1 | CARBOPYRONONE COMPOUNDS USEFUL AS DIAGNOSTIC ADJUVANTS | Life Technologies Corporation (US) | 2017-02-16 | — | — | US | claimed |
| US-20170044372-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation | 2017-02-16 | — | — | US | claimed |
| WO-2016209753-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation (US) | 2016-12-29 | — | — | WO | claimed |
| WO-2015175870-A1 | CARBOPYRONONE COMPOUNDS USEFUL AS DIAGNOSTIC ADJUVANTS | Life Technologies Corporation (US) | 2015-11-19 | — | — | WO | claimed |
| EP-0071985-B1 | WATER-SOLUBLE MONO-AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0071985-A2 | Water-soluble mono-azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | claimed |
| US-4046754-A | NATURAL FIBERS, POLYAMIDES, REGENERATED CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324198-A1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | SRI, SI, IK | ALDH1A1 1849/4885CYP3A4 797/4885THRB 2646/4885 |
| US-20170045496-A1 | CARBOPYRONONE COMPOUNDS USEFUL AS DIAGNOSTIC ADJUVANTS | MKI67, CYTH3, CYTH2 | ALDH1A1 2229/4885CYP3A4 2779/4885THRB 2117/4885 |
| US-20170044372-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | MKI67, DCX, NES | ALDH1A1 340/4885CYP3A4 3905/4885THRB 2163/4885 |
| US-20200408739-A1 | Carbopyronone Compounds Useful as Diagnostic Adjuvants | MKI67, CYTH3, CYTH2 | ALDH1A1 2229/4885CYP3A4 2779/4885THRB 2117/4885 |
| US-10739330-B2 | Carbopyronone compounds useful as diagnostic adjuvants | MKI67, CYTH3, CYTH2 | ALDH1A1 2229/4885CYP3A4 2779/4885THRB 2117/4885 |
| US-10018617-B2 | Carbopyronone compounds useful as diagnostic adjuvants | MKI67, CYTH3, CYTH2 | ALDH1A1 2229/4885CYP3A4 2779/4885THRB 2117/4885 |
| US-20180340928-A1 | Carbopyronone Compounds Useful as Diagnostic Adjuvants | MKI67, CYTH3, CYTH2 | ALDH1A1 2229/4885CYP3A4 2779/4885THRB 2117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.