Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526319 | 0.76 | PDK2 (0.48) | MEN1KMT2ASLC6A2SLC6A4HTR1A | |
| SCHEMBL23064484 | 0.76 | HTR1A (0.38) | NOS1GAAMEN1KMT2ACHRNA7 | |
| SCHEMBL24775518 | 0.76 | GAA (0.36) | NOS1GAAMEN1KMT2ACHRNA7 | |
| SCHEMBL2462253 | 0.72 | NOS1 (0.36) | NOS1GAAMEN1KMT2AKDM4E | |
| SCHEMBL15966936 | 0.72 | IDO1 (0.41) | NOS1GAAKDM4EALDH1A1KCNH2 | |
| SCHEMBL15966960 | 0.72 | RECQL (0.40) | GAAKDM4EALDH1A1NOTUMHTR2C | |
| SCHEMBL29139949 | 0.72 | NOS1 (0.43) | NOS1GAACHRNA7KDM4EALDH1A1 | |
| SCHEMBL484011 | 0.72 | KMT2A (0.44) | NOS1GAAMEN1KMT2ACHRNA7 | |
| SCHEMBL23064483 | 0.72 | KEAP1 (0.48) | GAAMEN1KMT2ACHRNA7KDM4E | |
| SCHEMBL31198346 | 0.72 | KEAP1 (0.48) | GAAMEN1KMT2ACHRNA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101756-B1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | claimed |