Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | CDH1 | P12830 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375802 | 0.83 | ALDH1A1 (0.61) | NPC1RAB9AMAPTTDP1HPGD | |
| SCHEMBL8375671 | 0.81 | NOTUM (0.56) | NOTUMNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2959768 | 0.80 | NPC1 (0.56) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL38657732 | 0.80 | PTPN1 (0.61) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8377265 | 0.80 | NPC1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8380106 | 0.80 | RAB9A (0.57) | NOTUMNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL788874 | 0.80 | ALDH1A1 (0.44) | NOTUMNPC1RAB9ACDH1CTNNB1 | |
| SCHEMBL8375633 | 0.79 | RAB9A (0.54) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8375803 | 0.79 | THRB (0.51) | NOTUMNPC1RAB9ACDH1CTNNB1 | |
| SCHEMBL5157687 | 0.79 | RAB9A (0.61) | NOTUMNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757042-B1 | Ortho-substituted 2-methoxyiminophenylaceticacid methylester | BASF AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| US-6605631-B1 | Controlling fungi and pests; improved activity and plant tolerability | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-12 | — | — | US | disclosed |
| US-6031110-A | Ortho-substituted 2-methoxyiminophenyl-N-methylacetamides | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| CN-1216986-A | Isoxazole derivatives | SANKYO CO (JP) | 1999-05-19 | — | — | CN | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0686152-B1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0757042-A1 | Ortho-substituted 2-methoxyiminophenylaceticacid methylester | BASF Aktiengesellschaft (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0686152-A1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AG (DE) | 1995-12-13 | — | — | EP | disclosed |
| EP-0405905-B1 | Use of Isoxazolin-3-one Derivatives as antidepressants | SANKYO CO (JP) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019331-A1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-01 | — | — | WO | disclosed |
| US-5262413-A | Aminoalkyloxy derivatives | SANKYO COMPANY, LIMITED (JP) | 1993-11-16 | — | — | US | disclosed |
| US-5217970-A | Use of isoxazolin-3-one derivatives as antidepressants | SANKYO COMPANY, LIMITED (JP) | 1993-06-08 | — | — | US | disclosed |
| US-5116839-A | Treatment of senility | SANKYO COMPANY, LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0405905-A2 | Use of Isoxazolin-3-one Derivatives as antidepressants | Sankyo Company Limited (JP) | 1991-01-02 | — | — | EP | disclosed |