Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.73 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.72 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.72 |
| ▸ | F2 | P00734 | 1/20 | 0.72 |
| ▸ | PLG | P00747 | 1/20 | 0.72 |
| ▸ | C1S | P09871 | 1/20 | 0.72 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.57 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8045403 | 0.98 | ITGB3 (0.71) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL1329642 | 0.84 | F2 (1.00) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL4022608 | 0.83 | PLA2G10 (0.61) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL24263917 | 0.82 | F2 (0.65) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7310517 | 0.82 | F2 (0.65) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7295273 | 0.81 | F10 (0.58) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11682104 | 0.80 | PRSS1 (0.62) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7118598 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL69614 | 0.79 | CA2 (0.79) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL11409409 | 0.79 | F2 (0.71) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| EP-0572560-B1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 2003-01-29 | — | — | EP | claimed |
| EP-0572560-A4 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY. | SHAPIRO HOWARD K (US) | 1995-04-26 | — | — | EP | claimed |
| EP-0572560-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO, Howard, K. (US) | 1993-12-08 | — | — | EP | claimed |
| WO-1992014456-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 1992-09-03 | — | — | WO | claimed |
| US-20220169621-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-06-02 | — | — | US | disclosed |
| US-20200354326-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2020-11-12 | — | — | US | disclosed |
| WO-2019150219-A2 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2019-08-08 | — | — | WO | disclosed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
| EP-0572560-B1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1056773-A2 | ANGIOGENESIS TARGETING MOLECULES | RESOLUTION PHARMACEUTICALS INC. (CA) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999040947-A2 | ANGIOGENESIS TARGETING MOLECULES | RESOLUTION PHARMACEUTICALS INC. (CA) | 1999-08-19 | — | — | WO | disclosed |
| EP-0572560-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO, Howard, K. (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0560730-A2 | New derivatives of beta-amino acids with anti-thrombotic activity | SANDOZ LTD. (CH) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992014456-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4018933-A | PENICILLINS; BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-4016159-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354326-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | OXA1L, CYP51A1, CYP1A1 | ITGB3 2337/4885ITGA2B 3006/4885PRSS1 3533/4885 |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | ITGB3 292/4885ITGA2B 117/4885PRSS1 34/4885 |
| US-20220169621-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | OXA1L, CYP51A1, CYP1A1 | ITGB3 2337/4885ITGA2B 3006/4885PRSS1 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.