Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942406 | 0.81 | HPGD (0.57) | CTSDKMT2AL3MBTL1HPGDHSD17B10 | |
| SCHEMBL6939482 | 0.79 | KMT2A (0.50) | CTSDKMT2AL3MBTL1HPGDHSD17B10 | |
| SCHEMBL11427578 | 0.79 | CYP1A2 (0.45) | CA1CA2CA9KMT2AL3MBTL1 | |
| SCHEMBL6939026 | 0.78 | KMT2A (0.63) | KMT2AL3MBTL1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL6935895 | 0.77 | CTSD (0.46) | CTSDCA1CA2CA9KMT2A | |
| SCHEMBL6564706 | 0.76 | PTGS2 (0.54) | CTSDKMT2AL3MBTL1HPGDHSD17B10 | |
| SCHEMBL6937373 | 0.75 | KMT2A (0.70) | CA2KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL6564711 | 0.74 | PTGS2 (0.55) | KMT2AL3MBTL1HPGDHSD17B10POLB | |
| SCHEMBL6939214 | 0.73 | CTSD (0.49) | CTSDCA1CA2CA9KMT2A | |
| SCHEMBL6934863 | 0.73 | LMNA (0.46) | CTSDKMT2AL3MBTL1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |