Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | INMT | O95050 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103778 | 0.77 | TSHR (0.39) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL419054 | 0.77 | TSHR (0.39) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL23181015 | 0.73 | TSHR (0.37) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL11453419 | 0.71 | TSHR (0.35) | TSHRTRIM24TRIM33L3MBTL1INMT | |
| SCHEMBL13868021 | 0.70 | L3MBTL1 (0.36) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL23051029 | 0.70 | TSHR (0.34) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL13813446 | 0.70 | TSHR (0.34) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL4657263 | 0.69 | L3MBTL1 (0.35) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL13460182 | 0.69 | RAB9A (0.45) | TSHRTRIM24TRIM33RAB9AL3MBTL1 | |
| SCHEMBL31055636 | 0.69 | HDAC6 (0.37) | KDM4ENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306654-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-09-29 | — | — | US | disclosed |
| CN-109641854-A | Integration stress access regulator | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105873911-B | Thiazolium compounds and its Pesticidal purposes | 住友化学株式会社 | 2018-07-24 | — | — | CN | disclosed |
| CN-104829605-B | 1 substitution 5 trifluoromethyl 4 pyrazoles joins 1,3,4 oxadiazole thioethers or sulfone derivatives and its application | 贵州大学 | 2018-03-23 | — | — | CN | disclosed |
| CN-105452241-B | Carboxamides derivatives of ((base of pyrimidine 4) epoxide) 1H indoles 1 and application thereof | 诺华股份有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-105431413-B | Glyoxylamide-substituted pyrrole amide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-01-02 | — | — | CN | disclosed |
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA LTD (CH) | 2017-11-09 | — | — | US | disclosed |
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA LTD (CH) | 2017-11-09 | — | — | US | disclosed |
| US-9809596-B1 | Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis | LONZA LTD. (CH) | 2017-11-07 | — | — | US | disclosed |
| US-9809596-B1 | Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis | LONZA LTD. (CH) | 2017-11-07 | — | — | US | disclosed |
| US-9802927-B2 | Oxadiazine compounds and methods of use thereof | DENALI THERAPEUTICS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170066753-A1 | OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF | DENALI THERAPEUTICS, INC. | 2017-03-09 | — | — | US | disclosed |
| WO-2017031325-A1 | OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF | FORUM PHARMACEUTICALS INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| US-20170050980-A1 | OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF | DENALI THERAPEUTICS, INC. | 2017-02-23 | — | — | US | disclosed |
| WO-2016201168-A1 | OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF | FORUM PHARMCEUTICALS INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| CN-105873911-A | Thiazole compounds and pest control applications thereof | 住友化学株式会社 | 2016-08-17 | — | — | CN | disclosed |
| EP-1061072-B1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA SRL (IT) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | AOC1, HDHD5, DDT | TSHR 611/4885TRIM24 4334/4885TRIM33 4743/4885 |
| US-20220306654-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | PIEZO1, PPOX, TAOK1 | TSHR 4009/4885TRIM24 2964/4885TRIM33 2489/4885 |
| US-20170066753-A1 | OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF | PSEN2, SMN1; SMN2, OTC | TSHR 4432/4885TRIM24 4492/4885TRIM33 2472/4885 |
| US-20170050980-A1 | OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF | PSEN2, SMN1; SMN2, OTC | TSHR 4432/4885TRIM24 4492/4885TRIM33 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.