SCHEMBL6941291

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12111153	0.83	GAA (0.56)	PDE10ATPH1TPH2BRS3MEN1
	SCHEMBL6941285	0.77	PKM (0.44)	PDE10APKMBRS3MEN1KMT2A
	Hydrochloric Acid SCHEMBL27136123	0.76	PDE10A (0.56)	PDE10APKMTPH1TPH2BRS3
	SCHEMBL16188974	0.76	KMT2A (0.64)	PDE10APKMMEN1KMT2AMAPT
	SCHEMBL8325831	0.74	PKM (0.54)	PDE10APKMRAB9AMEN1KMT2A
	SCHEMBL3478941	0.74	CHRNB2 (0.45)	PDE10APKMNPC1RAB9AMEN1
	SCHEMBL21034664	0.74	AAK1 (0.50)	PDE10ATPH1TPH2BRS3NPC1
	SCHEMBL12111158	0.73	GAA (0.56)	PDE10ATPH1TPH2BRS3MEN1
	SCHEMBL7332580	0.72	F10 (0.53)	PDE10APKMNPC1RAB9AMEN1
	SCHEMBL16188989	0.71	GAA (0.53)	PDE10APKMMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.