SCHEMBL6942417

SCHEMBL6942417

CC(C)(C)CC(C)(C)c1cccc(C(C)(C)CC(C)(C)C)c1O.CCC(C)c1cc(C)ccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.47
TSHR P16473 2/20 0.40
CHRM1 P11229 3/20 0.36
LMNA P02545 2/20 0.36
ADRA1A P35348 2/20 0.36
CHRM2 P08172 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM3 P20309 2/20 0.36
HRH1 P35367 2/20 0.36
ESR1 P03372 1/20 0.36
CHRM4 P08173 1/20 0.36
MAPT P10636 1/20 0.36
KCNE1 P15382 1/20 0.36
PTGS1 P23219 1/20 0.36
HRH2 P25021 1/20 0.36
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
OPRK1 P41145 1/20 0.36
KCNQ1 P51787 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6939529 0.78 RORC (0.59) RORCTSHRCHRM1LMNAADRA1A
SCHEMBL9250563 0.76 TSHR (0.57) RORCTSHRHDAC4HDAC2HDAC8
SCHEMBL1833403 0.75 CA2 (0.56) TSHRESR1PTGS1GAAKMT2A
SCHEMBL2787846 0.72 TRPA1 (0.45) TSHRLMNAESR1MAPTPTGS1
SCHEMBL30553420 0.72 TRPA1 (0.45) TSHRLMNAESR1MAPTPTGS1
SCHEMBL10348751 0.71 ALDH1A1 (0.38) RORCTSHRMAPTHDAC4HDAC2
SCHEMBL11235624 0.71 LMNA (0.38) TSHRCHRM1LMNAADRA1ACHRM2
SCHEMBL3216750 0.70 CA2 (0.45) TSHRLMNAMAPTTRPA1CA2
SCHEMBL31108089 0.69 TRPA1 (0.45) CHRM1LMNAADRA1AESR1MAPT
SCHEMBL2911405 0.69 GABRA1 (0.62) TSHRMAPTCNR1CNR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866112-B1 Sulfurized phenolic antioxidant composition, method of preparing same, and petroleum products containing same ETHYL CORP (US) 2000-03-29 EP claimed
US-6001786-A A THIOPHENOL STABILIZER IS PREPARED BY REACTING AT LEAST TWO DIFFERENT CHLORINE-FREE HINDERED PHENOLS, A CHLORINE-FREE SULFUR SOURCE AND ALKALI METAL HYDROXIDE PROMOTER IN PROPANOL SOLVENT; FOR LUBRICATING OILS AND LIQUID ORGANIC FUELS ETHYL CORPORATION (US) 1999-12-14 US claimed
EP-0866112-A1 Sulfurized phenolic antioxidant composition, method of preparing same, and petroleum products containing same ETHYL CORPORATION (US) 1998-09-23 EP claimed
EP-0811631-B1 Sulfurized phenolic antioxidant composition, method of preparing same, and petroleum products containing same ETHYL CORP (US) 2003-02-19 EP disclosed
US-6096695-A CHLORINE-FREE LUBRICANT OIL ADDITIVE PREPARED BY REACTION OF HINDERED PHENOLS WITH SULFUR IN PRESENCE OF ALKALI METAL HYDROXIDE PROMOTER ETHYL CORPORATION (US) 2000-08-01 US disclosed
EP-0866112-B1 Sulfurized phenolic antioxidant composition, method of preparing same, and petroleum products containing same ETHYL CORP (US) 2000-03-29 EP disclosed
US-6001786-A A THIOPHENOL STABILIZER IS PREPARED BY REACTING AT LEAST TWO DIFFERENT CHLORINE-FREE HINDERED PHENOLS, A CHLORINE-FREE SULFUR SOURCE AND ALKALI METAL HYDROXIDE PROMOTER IN PROPANOL SOLVENT; FOR LUBRICATING OILS AND LIQUID ORGANIC FUELS ETHYL CORPORATION (US) 1999-12-14 US disclosed
EP-0866112-A1 Sulfurized phenolic antioxidant composition, method of preparing same, and petroleum products containing same ETHYL CORPORATION (US) 1998-09-23 EP disclosed
EP-0811631-A2 Sulfurized phenolic antioxidant composition, method of preparing same, and petroleum products containing same ETHYL CORPORATION (US) 1997-12-10 EP disclosed