SCHEMBL6942558

SCHEMBL6942558

CCCc1cccc(CCC)c1N=C=O

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.74
GABRB2 P47870 4/20 0.74
CYP3A4 P08684 2/20 0.41
DAO P14920 1/20 0.39
TSHR P16473 1/20 0.32
ELANE P08246 2/20 0.32
IAPP P10997 1/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
GRM5 P41594 1/20 0.31
CTSG P08311 1/20 0.31
HTR1A P08908 1/20 0.31
BID P55957 3/20 0.30
MCL1 Q07820 3/20 0.30
BCL2L1 Q07817 2/20 0.30
BAK1 Q16611 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10613392 0.96 GABRA1 (0.81) GABRA1GABRB2CYP3A4DAOTSHR
SCHEMBL11732170 0.89 GABRA1 (0.59) GABRA1GABRB2CYP3A4DAO
SCHEMBL8156690 0.89 GABRA1 (0.59) GABRA1GABRB2CYP3A4DAOTSHR
SCHEMBL10614732 0.88 GABRA1 (0.58) GABRA1GABRB2CYP3A4DAO
SCHEMBL10613242 0.88 GABRA1 (0.58) GABRA1GABRB2CYP3A4DAOTSHR
SCHEMBL10613027 0.88 GABRA1 (0.62) GABRA1GABRB2CYP3A4DAOPPARG
SCHEMBL9622722 0.85 GABRA1 (0.65) GABRA1GABRB2PPARGPPARABID
SCHEMBL18258702 0.85 GABRA1 (0.52) GABRA1GABRB2DAOELANEIAPP
SCHEMBL1457739 0.85 GABRA1 (1.00) GABRA1GABRB2CYP3A4DAOTSHR
SCHEMBL28007487 0.85 GABRA1 (0.54) GABRA1GABRB2CYP3A4DAOTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578664-B2 Toner and method for producing toner CANON KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
US-12535750-B2 Toner CANON KABUSHIKI KAISHA (JP) 2026-01-27 US disclosed
US-12429789-B2 Toner and method for producing toner CANON KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
US-12386278-B2 Toner and method for producing toner CANON KABUSHIKI KAISHA (JP) 2025-08-12 US disclosed
US-12351542-B2 Spacered urea (meth)acrylates EVONIK OPERATIONS GMBH (DE) 2025-07-08 US disclosed
US-12338202-B2 One pot synthesis of urea (meth)acrylates EVONIK OPERATIONS GMBH (DE) 2025-06-24 US disclosed
US-12298709-B2 Toner and method for producing toner CANON KABUSHIKI KAISHA (JP) 2025-05-13 US disclosed
CN-114637173-B Toner and method for producing toner 佳能株式会社 2025-01-24 CN disclosed
CN-110597029-B Toner and method for producing toner 佳能株式会社 2025-01-03 CN disclosed
CN-110597033-B Toner and method for producing toner 佳能株式会社 2024-12-27 CN disclosed
CN-110597031-A Toner and image forming apparatus 佳能株式会社 2019-12-20 CN disclosed
CN-110597033-A Toner and method for producing toner 佳能株式会社 2019-12-20 CN disclosed
CN-110597027-A Toner and method for producing toner 佳能株式会社 2019-12-20 CN disclosed
CN-110597030-A Toner and two-component developer 佳能株式会社 2019-12-20 CN disclosed
CN-110597028-A Magnetic toner and method for producing magnetic toner 佳能株式会社 2019-12-20 CN disclosed
CN-109952539-A Toner binder for electrophotography and toner composition 三洋化成工业株式会社 2019-06-28 CN disclosed
EP-1042278-B1 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF SLOVAKOFARMA AS (SK) 2003-03-05 EP disclosed
US-6444691-B1 ANTICHOLESTEROL AGENTS SOLVAKOFARMA, A.S. (SK) 2002-09-03 US disclosed
EP-1042278-A1 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF Slovakofarma, A.S. (SK) 2000-10-11 EP disclosed
WO-1999032437-A1 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF SLOVAKOFARMA, A.S. (SK) 1999-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351542-B2 Spacered urea (meth)acrylates METTL14, METTL3, FUS GABRA1 459/4885GABRB2 1101/4885CYP3A4 3343/4885
US-12338202-B2 One pot synthesis of urea (meth)acrylates ADH1A, ADH1C, METTL14 GABRA1 2645/4885GABRB2 3364/4885CYP3A4 460/4885
US-12578664-B2 Toner and method for producing toner C1R, TECR, FCGR2A GABRA1 126/4885GABRB2 561/4885CYP3A4 1449/4885
US-12535750-B2 Toner TAS1R3, TAS2R3, TAS2R43 GABRA1 258/4885GABRB2 984/4885CYP3A4 2842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.