Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL28439673 | 0.86 | ALDH1A1 (0.46) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL1596054 | 0.85 | TDP1 (0.56) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL5904485 | 0.84 | TDP1 (0.48) | TDP1TSHRALDH1A1MAPK1 | |
| Isobutanol SCHEMBL30450802 | 0.83 | TSHR (0.64) | TDP1TSHRALDH1A1DPP4 | |
| Propylene Glycol SCHEMBL161401 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL7522896 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL15864609 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL28578 | 0.82 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNATHRB | |
| Propylene Glycol SCHEMBL3535 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223352-B1 | DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS | UROTRONIC INC (US) | 2026-05-27 | — | — | EP | claimed |
| US-20260139088-A1 | PROCESS FOR PREPARATION OF MONODISPERSE PARTICLES | N-lab Technology Center Pte, Ltd. (SG) | 2026-05-21 | — | — | US | claimed |
| WO-2026101451-A1 | SUPERPARAMAGNETIC MICROSPHERES AND METHOD FOR THE PRODUCTION THEREOF | N-LAB TECHNOLOGY CENTER PTE. LTD. (SG) | 2026-05-15 | — | — | WO | claimed |
| US-12605342-B2 | Polymer-encapsulated drug particles | TONIC MEDICAL, INC. (US) | 2026-04-21 | — | — | US | claimed |
| EP-4146381-B1 | SUPERPARAMAGNETIC MONODISPERSE PARTICLES AND METHOD FOR THE PRODUCTION THEREOF | N LAB TECH CENTER PTE LTD (SG) | 2026-04-08 | — | — | EP | claimed |
| US-20250388769-A1 | Ink Composition, Package Structure and Semiconductor Device | HANGZHOU FIRST APPLIED MAT CO LTD (CN) | 2025-12-25 | — | — | US | claimed |
| US-20250339654-A1 | DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS | UROTRONIC INC (US) | 2025-11-06 | — | — | US | claimed |
| US-12460122-B2 | Composition that can be used to delay the formation of gas hydrates | ARKEMA FRANCE (FR) | 2025-11-04 | — | — | US | claimed |
| US-12415878-B2 | Benzyl (meth)acrylate monomers suitable for microstructured optical films | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-09-16 | — | — | US | claimed |
| US-12357732-B2 | Drug coated balloon catheters for nonvascular strictures | UROTRONIC, INC. (US) | 2025-07-15 | — | — | US | claimed |
| CN-114853799-A | Compound and composition for film packaging and packaging film | 吉林奥来德光电材料股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| US-11359118-B2 | Adhesive composition having excellent kisstack | LG CHEM, LTD. | 2022-06-14 | — | — | US | claimed |
| CN-112571893-B | Photochromic glass and preparation method thereof | 上海甘田光学材料有限公司 | 2022-06-03 | — | — | CN | claimed |
| EP-3997172-A1 | THIOL-BASED ADHESIVE FORMULATIONS FOR REPAIRING WINDSHIELDS | Mondofix Inc. (CA) | 2022-05-18 | — | — | EP | claimed |
| CN-114479735-A | Cationic UV curing adhesive and preparation method and application thereof | 张河远 | 2022-05-13 | — | — | CN | claimed |
| CN-112574605-B | Photochromic film and preparation method thereof | 上海甘田光学材料有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-110536941-B | Adhesive composition | 汉高知识产权控股有限责任公司 | 2022-04-19 | — | — | CN | claimed |
| CN-112724441-A | Photochromic optical element and preparation method thereof | 上海甘田光学材料有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112574605-A | Photochromic film and preparation method thereof | 上海甘田光学材料有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-112571893-A | Photochromic glass and preparation method thereof | 上海甘田光学材料有限公司 | 2021-03-30 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139088-A1 | PROCESS FOR PREPARATION OF MONODISPERSE PARTICLES | CD14, CD47, MYD88 | TDP1 1709/4885TSHR 1899/4885ALDH1A1 661/4885 |
| US-12605342-B2 | Polymer-encapsulated drug particles | MUC1, SLC10A2, EGFR | TDP1 4613/4885TSHR 455/4885ALDH1A1 3181/4885 |
| US-20250388769-A1 | Ink Composition, Package Structure and Semiconductor Device | ASH2L, INO80C, CCNL2 | TDP1 3492/4885TSHR 4295/4885ALDH1A1 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.