SCHEMBL694362

SCHEMBL694362

CNCCCNC(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.65
MEN1 O00255 1/20 0.61
GAA P10253 1/20 0.61
KMT2A Q03164 1/20 0.61
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
CA1 P00915 9/20 0.53
CA2 P00918 9/20 0.53
CA12 O43570 6/20 0.53
CA9 Q16790 6/20 0.53
STK17B O94768 1/20 0.47
STK17A Q9UEE5 1/20 0.47
EPHX1 P07099 1/20 0.45
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 1/20 0.40
GFER P55789 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL17818451 0.98 TDP1 (0.62) TDP1MEN1GAAKMT2AMAOA
Hydrochloric Acid SCHEMBL30183864 0.98 TDP1 (0.62) TDP1MEN1GAAKMT2AMAOA
SCHEMBL691053 0.96 TDP1 (0.70) TDP1MEN1GAAKMT2AMAOA
SCHEMBL14571199 0.94 TDP1 (0.73) TDP1MEN1GAAKMT2AMAOA
SCHEMBL21996829 0.94 TDP1 (0.73) TDP1MEN1GAAKMT2AMAOA
SCHEMBL12772839 0.94 TDP1 (0.73) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1588079 0.94 TDP1 (0.73) TDP1MEN1GAAKMT2AMAOA
SCHEMBL569251 0.92 TDP1 (0.74) TDP1MEN1GAAKMT2AMAOA
SCHEMBL7771476 0.88 TDP1 (0.56) TDP1MEN1GAAKMT2AMAOA
SCHEMBL46654 0.88 TDP1 (0.58) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747243-A1 LIGANDS AND COMPOSITIONS AND METHODS OF USE THEREOF Baylor College of Medicine (US) 2026-05-27 EP disclosed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
CN-122036541-A Amino acid-based ionizable lipid compound, and preparation method and application thereof 中国科学院广州生物医药与健康研究院 2026-05-15 CN disclosed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
EP-3983081-B1 AMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS LLC (US) 2026-03-11 EP disclosed
EP-4703355-A1 FLUORINE-CONTAINING ISOXAZOLONE COMPOUND AND PRODUCTION METHOD FOR SAME Unimatec Co., Ltd. (JP) 2026-03-04 EP disclosed
EP-4687854-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY Flagship Labs 114, Inc. (US) 2026-02-11 EP disclosed
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCE INC (US) 2026-02-05 US disclosed
US-20260014261-A1 TARGETED PROTEIN MODIFICATION WEATHERWAX BIOTECHNOLOGIES CORP (US) 2026-01-15 US disclosed
US-20260007668-A1 AMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS LLC (US) 2026-01-08 US disclosed
EP-1817030-A2 INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS Kalypsys, Inc. (US) 2007-08-15 EP disclosed
WO-2007062411-A1 NOVEL METHOD OF PREPARATION OF 5-CHLORO-3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOLE AND (3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOL-5-YL)-DIALKYL-AMINES KALYPSYS, INC. (US) 2007-05-31 WO disclosed
US-20070123572-A1 NOVEL METHOD OF PREPARATION OF 5-CHLORO-3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOLE AND (3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOL-5YL)-DIALKYL-AMINES KALYPSYS, INC. (US) 2007-05-31 US disclosed
US-20070123572-A1 NOVEL METHOD OF PREPARATION OF 5-CHLORO-3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOLE AND (3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOL-5YL)-DIALKYL-AMINES KALYPSYS, INC. (US) 2007-05-31 US disclosed
WO-2006097260-A1 ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY NOVARTIS AG (CH) 2006-09-21 WO disclosed
WO-2006060424-A2 INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS KALYPSYS, INC. (US) 2006-06-08 WO disclosed
US-20060116515-A1 Inducible nitric oxide synthase dimerization inhibitors KALYPSYS, INC. 2006-06-01 US disclosed
US-20060094724-A1 Fused furan compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2006-05-04 US disclosed
EP-1582521-A1 FUSED FURAN COMPOUND TANABE SEIYAKU CO., LTD. (JP) 2005-10-05 EP disclosed
WO-2004026846-A1 DNA-TARGETED BENZOTRIAZINE 1,4-DIOXIDES AND THEIR USE IN CANCER THERAPY AUCKLAND UNISERVICES LIMITED (NZ) 2004-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123572-A1 NOVEL METHOD OF PREPARATION OF 5-CHLORO-3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOLE AND (3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOL-5YL)-DIALKYL-AMINES DCLK2, TH, DCLK3 TDP1 528/4885MEN1 1611/4885GAA 4103/4885
US-20060116515-A1 Inducible nitric oxide synthase dimerization inhibitors NOS3, NOS2, NOS1 TDP1 3765/4885MEN1 4731/4885GAA 4162/4885
US-20260007668-A1 AMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF BECN1, SQSTM1, ATG7 TDP1 480/4885MEN1 4048/4885GAA 2406/4885
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF BCL2L2, BCL2A1, BCL2L1 TDP1 3952/4885MEN1 3960/4885GAA 3879/4885
US-20260014261-A1 TARGETED PROTEIN MODIFICATION MDM2, TP53, VHL TDP1 1244/4885MEN1 2924/4885GAA 949/4885
US-20060094724-A1 Fused furan compound F2, F12, F11 TDP1 4423/4885MEN1 1870/4885GAA 4234/4885
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION CCR10, CCR1, CCR3 TDP1 3130/4885MEN1 4805/4885GAA 3539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.