Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579495 | 0.73 | CA1 (0.44) | ALDH1A1HPGDMAPTHTTLMNA | |
| SCHEMBL2490664 | 0.72 | SIGMAR1 (0.57) | ALDH1A1MAPTTDP1KDM4ERAB9A | |
| SCHEMBL8485436 | 0.70 | KCNJ1 (0.66) | ALDH1A1HPGDKCNJ1NOTUMMAPT | |
| SCHEMBL1163779 | 0.70 | NOTUM (0.64) | ALDH1A1HPGDKCNJ1NOTUMMAPT | |
| SCHEMBL1663879 | 0.67 | KCNJ1 (1.00) | ALDH1A1HPGDKCNJ1NOTUMMAPT | |
| SCHEMBL311636 | 0.66 | MAPT (1.00) | ALDH1A1HPGDKCNJ1NOTUMMAPT | |
| SCHEMBL82595 | 0.66 | MAPT (0.69) | ALDH1A1KCNJ1NOTUMMAPTF2 | |
| SCHEMBL11716535 | 0.65 | NOTUM (0.62) | ALDH1A1HPGDKCNJ1NOTUMMAPT | |
| SCHEMBL8670043 | 0.65 | LIPE (0.33) | POLBL3MBTL1 | |
| SCHEMBL14919144 | 0.65 | NOTUM (0.61) | ALDH1A1KCNJ1NOTUMMAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973768-B1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-09 | — | — | EP | claimed |
| EP-0973768-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | claimed |
| WO-1998043970-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-08 | — | — | WO | claimed |