Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040592 | 0.90 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL9040433 | 0.90 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL9728223 | 0.88 | DPP8 (0.46) | NPBWR1MCHR1DPP8DPP9TDP1 | |
| SCHEMBL9119637 | 0.88 | DPP8 (0.45) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8440008 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8435956 | 0.86 | PDK1 (0.45) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8435953 | 0.86 | PDK1 (0.45) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8588093 | 0.86 | PDK1 (0.45) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL9120984 | 0.86 | OPRK1 (0.39) | ALDH1A1OPRK1LMNANPBWR1MCHR1 | |
| SCHEMBL8434820 | 0.86 | TDP1 (0.43) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |