Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.61 |
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192380 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL27827028 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL27473286 | 0.79 | LMNA (0.60) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL27761128 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL1426459 | 0.79 | NPC1 (0.46) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL6237542 | 0.79 | TSHR (0.41) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL12157631 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL6558492 | 0.78 | CTSD (0.56) | ALDH1A1HSD17B10HPGDGAAMAPT | |
| SCHEMBL3304359 | 0.78 | RAB9A (0.44) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL28002678 | 0.78 | POLB (0.50) | ALDH1A1HPGDMAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136349-B2 | Decarboxylative conjugate additions and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-10-05 | — | — | US | disclosed |
| CN-107531660-A | α cinnamide compounds and composition as HDAC8 inhibitor | 福马治疗股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| EP-1335898-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | Prolifix Limited (GB) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002026696-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |
| CN-1022187-C | Method for preparation of tricyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-09-22 | — | — | CN | disclosed |
| CN-1040981-A | Tricyclic compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1990-04-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136349-B2 | Decarboxylative conjugate additions and applications thereof | PTMS, DNPEP, QPCT | ALDH1A1 436/4885HSD17B10 1573/4885CFTR 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.