Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258996 | 0.83 | CA2 (0.42) | ALDH1A1CA2SMN1; SMN2LPLLIPG | |
| SCHEMBL513841 | 0.82 | AGXT (0.52) | CYP2A6ALDH1A1CA2TAAR1MAPT | |
| SCHEMBL2090223 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CA2TP53SMN1; SMN2PLK1 | |
| SCHEMBL10902822 | 0.79 | DHFR (0.37) | SOD1 | |
| SCHEMBL9256358 | 0.79 | SOD1 (0.43) | CYP2A6ALDH1A1SOD1TDP1TP53 | |
| SCHEMBL208838 | 0.79 | NQO1 (0.54) | ALDH1A1TDP1CA2SMN1; SMN2LMNA | |
| SCHEMBL3092949 | 0.79 | IDO1 (0.50) | ALDH1A1CA2TAAR1CYP2C19KMT2A | |
| SCHEMBL6341 | 0.78 | IDO1 (0.55) | CA2TAAR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5543889 | 0.78 | CA1 (0.61) | ALDH1A1TDP1CA2SMN1; SMN2LMNA | |
| SCHEMBL8816 | 0.77 | IDO1 (0.52) | ALDH1A1CA2TAAR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177168-A4 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA INC (US) | 2003-06-25 | — | — | EP | claimed |
| JP-2002541237-A | — | — | 2002-12-03 | — | — | JP | claimed |
| EP-1177168-A1 | CASPASE INHIBITORS AND THE USE THEREOF | Cytovia, Inc. (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000061542-A1 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2000-10-19 | — | — | WO | claimed |
| EP-1177168-A4 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA INC (US) | 2003-06-25 | — | — | EP | disclosed |
| EP-1177168-A1 | CASPASE INHIBITORS AND THE USE THEREOF | Cytovia, Inc. (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000061542-A1 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0331394-B1 | PROCESS FOR PREPARING 2 BETA-SUBSTITUTED-METHYLPENICILLIN DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0272016-B1 | 2BETA-SUBSTITUTED-METHYLPENICILLANIC ACID DERIVATIVES, AND SALTS AND ESTERS THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0273599-B1 | PROCESS FOR PREPARING 2BETA-SUBSTITUTED-METHYL-PENICILLIN DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-4933444-A | Process for preparing 2β-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4898939-A | Process for preparing 2β-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4891369-A | BETA-LACTAMASE INHIBITORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0331394-A1 | Process for preparing 2 beta-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0272016-A1 | 2beta-substituted-methylpenicillanic acid derivatives, and salts and esters thereof | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-22 | — | — | EP | disclosed |