Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | MME | P08473 | 4/20 | 0.33 |
| ▸ | ACE | P12821 | 4/20 | 0.33 |
| ▸ | CPA1 | P15085 | 4/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948125 | 0.93 | ALDH1A1 (0.35) | TP53MAPT | |
| SCHEMBL6948070 | 0.85 | TP53 (0.35) | TP53PPARGMAPTPPARA | |
| SCHEMBL25764848 | 0.67 | TDP1 (0.52) | ITGB1ITGA4PPARGMMEACE | |
| SCHEMBL25764849 | 0.67 | TDP1 (0.52) | ITGB1ITGA4PPARGMMEACE | |
| SCHEMBL6947291 | 0.65 | DRD2 (0.36) | TP53 | |
| SCHEMBL16116802 | 0.64 | LDHA (0.63) | PPARGPPARA | |
| SCHEMBL839542 | 0.64 | LDHA (0.63) | PPARGPPARA | |
| SCHEMBL6483477 | 0.64 | PPARG (0.65) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL6954155 | 0.63 | PPARG (0.43) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL6952000 | 0.63 | ITGB3 (0.41) | ITGB1ITGA4ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |