Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TPH1 | P17752 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952116 | 0.84 | DRD2 (0.36) | DRD2DRD4DRD3S1PR5TPH1 | |
| SCHEMBL6953255 | 0.79 | PPARA (0.43) | HSD11B1 | |
| SCHEMBL25764848 | 0.69 | TDP1 (0.52) | TDP1KMT2A | |
| SCHEMBL25764849 | 0.69 | TDP1 (0.52) | TDP1KMT2A | |
| SCHEMBL6950764 | 0.65 | ITGB1 (0.36) | TP53 | |
| SCHEMBL23917908 | 0.64 | KMT2A (0.47) | TDP1MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1287829 | 0.61 | FOLH1 (0.61) | MEN1KMT2A | |
| SCHEMBL547121 | 0.61 | FOLH1 (0.61) | MEN1KMT2A | |
| SCHEMBL547122 | 0.61 | FOLH1 (0.61) | MEN1KMT2A | |
| SCHEMBL839840 | 0.61 | SIGMAR1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |