Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966403 | 0.86 | FYN (0.43) | MAPTALDH1A1MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6966648 | 0.84 | TP53 (0.41) | CHRNA7SMOMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6959299 | 0.82 | MEN1 (0.42) | CHRNA7MAPTHTR1APOLBGAA | |
| SCHEMBL6955336 | 0.81 | POLB (0.42) | MAPTALDH1A1SMN1; SMN2HTR1AHTR7 | |
| SCHEMBL6960766 | 0.80 | MAPT (0.35) | CHRNA7MAPTALDH1A1SMN1; SMN2PKM | |
| SCHEMBL6956633 | 0.79 | MAPT (0.44) | SMOMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6956780 | 0.79 | MAP4K1 (0.42) | CHRNA7MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6965770 | 0.77 | MAPT (0.42) | SMOMAPTALDH1A1HTR1AHTR7 | |
| SCHEMBL6961535 | 0.77 | KIT (0.47) | MAPTALDH1A1SMN1; SMN2HTR7HSD17B10 | |
| SCHEMBL6968664 | 0.77 | MAP4K1 (0.46) | CHRNA7MAPTALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |