Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966648 | 0.82 | TP53 (0.41) | MAPTLMNACHRNA7HPGDSMN1; SMN2 | |
| SCHEMBL6955336 | 0.81 | POLB (0.42) | MAPTKCNH2SMN1; SMN2POLBKDM4E | |
| SCHEMBL6961354 | 0.80 | CHRNA7 (0.37) | MAPTLMNARXFP1CHRNA7PKM | |
| SCHEMBL6959299 | 0.78 | MEN1 (0.42) | MAPTLMNASLC6A7CHRNA7PDE3B | |
| SCHEMBL6956780 | 0.75 | MAP4K1 (0.42) | MAPTCHRNA7HPGDTSHRSMN1; SMN2 | |
| SCHEMBL6956633 | 0.75 | MAPT (0.44) | MAPTLMNAPKMHPGDTSHR | |
| SCHEMBL6965770 | 0.75 | MAPT (0.42) | MAPTPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL6966403 | 0.75 | FYN (0.43) | MAPTLMNARXFP1HPGDTSHR | |
| SCHEMBL6961535 | 0.75 | KIT (0.47) | MAPTLMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL6952938 | 0.75 | MAP4K1 (0.41) | PDE3BPDE3AHPGDALDH1A1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |