Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097781 | 0.87 | ADRA2A (0.43) | ADRA2ANLRP3L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL8091499 | 0.86 | NLRP3 (0.40) | NLRP3L3MBTL1TDP1HTTALDH1A1 | |
| SCHEMBL8097787 | 0.83 | TSHR (0.40) | TDP1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL8091366 | 0.79 | NOTUM (0.43) | ADRA2AL3MBTL1TDP1ALDH1A1HPGD | |
| SCHEMBL1429298 | 0.75 | AKR1B1 (0.55) | ADRA2ANLRP3HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL27499925 | 0.74 | ADRA2A (0.50) | ADRA2ANOTUM | |
| Ammonia Solution, Strong SCHEMBL27532390 | 0.74 | AKR1B1 (0.53) | ADRA2ANLRP3HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8099968 | 0.71 | MCHR1 (0.42) | NLRP3L3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8092415 | 0.71 | BRD4 (0.39) | NLRP3L3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8092437 | 0.69 | ADRA2A (0.43) | ADRA2ANLRP3HTTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183907-C | Imidazoline compound, preparing process thereof and pharmaceutical composition contg. same | SERVIER LAB (FR) | 2005-01-12 | — | — | CN | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |