Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956175 | 0.77 | MTNR1B (0.37) | — | |
| SCHEMBL7080318 | 0.75 | MTNR1A (0.38) | CA12CA9CAPN1 | |
| SCHEMBL7083881 | 0.73 | — | — | |
| SCHEMBL6017700 | 0.70 | CAPN1 (0.40) | MAOASLC22A12CAPN1ATMRHEB | |
| SCHEMBL2852938 | 0.68 | TAAR1 (0.56) | MAOASLC22A12CAPN1ATM | |
| SCHEMBL23925823 | 0.62 | NPSR1 (0.41) | CA12CA9 | |
| SCHEMBL3393678 | 0.60 | PYGL (0.57) | CAPN1 | |
| SCHEMBL31420517 | 0.60 | NOS2 (0.39) | MAOASLC22A12CAPN1ATM | |
| SCHEMBL1429057 | 0.58 | HSD17B10 (0.38) | CA12CA9 | |
| SCHEMBL2469838 | 0.58 | TAAR1 (0.55) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | claimed |