Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 2/20 | 0.33 |
| ▸ | PAICS | P22234 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306207 | 0.94 | GPR55 (0.35) | FSCN1PAICSGPR55CNR1HTR4 | |
| SCHEMBL7799605 | 0.85 | GPR55 (0.34) | GPR55CNR1HTR4 | |
| SCHEMBL8307581 | 0.84 | GPR55 (0.38) | GPR55CNR1HTR4 | |
| SCHEMBL8308257 | 0.81 | NR3C1 (0.39) | GPR55CNR1HTR4 | |
| SCHEMBL8365008 | 0.80 | SMN1; SMN2 (0.39) | FSCN1GPR55CNR1CYP3A4CYP2D6 | |
| SCHEMBL8309066 | 0.79 | HTR4 (0.46) | GPR55HTR4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6962731 | 0.79 | MDM2 (0.37) | GPR55CNR1HTR4 | |
| SCHEMBL7749150 | 0.79 | MDM2 (0.37) | GPR55CNR1HTR4 | |
| SCHEMBL8307419 | 0.79 | HTR4 (0.36) | GPR55CNR1HTR4 | |
| SCHEMBL7799596 | 0.79 | HTR4 (0.36) | GPR55HTR4CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980368-B1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6248757-B1 | ANTISEROTONINE AGENTS | SANOFI-SYNTHELABO (FR) | 2001-06-19 | — | — | US | disclosed |