Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.37 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962731 | 1.00 | MDM2 (0.37) | MDM2PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL8308257 | 0.95 | NR3C1 (0.39) | PIK3CAPIK3CGMAPTGPR55NR3C1 | |
| SCHEMBL6956244 | 0.79 | FSCN1 (0.33) | GPR55HTR4CNR1 | |
| SCHEMBL8309066 | 0.78 | HTR4 (0.46) | GPR55HTR4THRB | |
| SCHEMBL8305942 | 0.77 | TP53 (0.40) | MAPTGPR55NR3C1CNR1CNR2 | |
| SCHEMBL8303784 | 0.76 | NR3C1 (0.39) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL6956182 | 0.69 | BCHE (0.36) | MAPTGPR55HTR4CNR1 | |
| SCHEMBL8517107 | 0.67 | TP53 (0.41) | GPR55CNR1TP53 | |
| SCHEMBL8303718 | 0.67 | HTR4 (0.52) | HTR4 | |
| SCHEMBL23273826 | 0.66 | MEN1 (0.46) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248757-B1 | ANTISEROTONINE AGENTS | SANOFI-SYNTHELABO (FR) | 2001-06-19 | — | — | US | disclosed |