Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 8/20 | 0.34 |
| ▸ | PAICS | P22234 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956244 | 0.94 | FSCN1 (0.33) | GPR55CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8307581 | 0.88 | GPR55 (0.38) | GPR55CNR1CNR2HTR4 | |
| SCHEMBL7799605 | 0.87 | GPR55 (0.34) | GPR55CNR1HTR4 | |
| SCHEMBL8365008 | 0.85 | SMN1; SMN2 (0.39) | GPR55CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8308257 | 0.84 | NR3C1 (0.39) | GPR55CNR1CNR2HTR4NR3C1 | |
| SCHEMBL8309066 | 0.83 | HTR4 (0.46) | GPR55CYP3A4CYP2D6CYP2C9HTR4 | |
| SCHEMBL8307419 | 0.82 | HTR4 (0.36) | GPR55CNR1HTR4 | |
| SCHEMBL8308109 | 0.82 | HTR4 (0.48) | HTR4 | |
| Bromide SCHEMBL8369628 | 0.81 | HTR4 (0.47) | HTR4 | |
| SCHEMBL7749150 | 0.81 | MDM2 (0.37) | GPR55CNR1CNR2HTR4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |