Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212064 | 0.84 | ENPP2 (0.53) | ACHEKMT2AMEN1MAPTUSP2 | |
| SCHEMBL4283301 | 0.76 | KMT2A (0.56) | ACHEKMT2AMEN1GAAMAPT | |
| SCHEMBL11398219 | 0.75 | MEN1 (0.36) | ACHEKMT2AMEN1GAAMAPT | |
| SCHEMBL11789844 | 0.75 | KMT2A (0.81) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL31161862 | 0.74 | ACHE (0.55) | ACHEKMT2AMEN1GAAMAPT | |
| SCHEMBL11513541 | 0.73 | NPC1 (0.58) | ACHEKMT2AMEN1GAAMAPT | |
| SCHEMBL5821824 | 0.72 | RAB9A (0.62) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL7212105 | 0.71 | L3MBTL1 (0.42) | ACHEHTTL3MBTL1HDAC6TSHR | |
| SCHEMBL23004832 | 0.71 | ACHE (0.58) | ACHEKMT2AMEN1GAAMAPT | |
| SCHEMBL13504059 | 0.71 | SLC6A3 (0.49) | ACHEKMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863877-A | Be used for the treatment of the treatment of pain agent | EURO CELTIQUE SA | 2010-10-20 | — | — | CN | disclosed |
| CN-1835751-B | Therapeutic agent for treating pain | EURO CELTIQUE SA | 2010-06-23 | — | — | CN | disclosed |
| CN-1835751-A | therapeutic agent for treating pain | EURO CELTIQUE SA (LU) | 2006-09-20 | — | — | CN | disclosed |
| EP-0898562-B1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | UPJOHN CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-5712300-A | ENZYME INHIBITOR | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-27 | — | — | US | disclosed |