Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201036 | 0.85 | MPO (0.61) | SLC6A4HTR2ATRPM8 | |
| SCHEMBL16432776 | 0.84 | SLC6A4 (0.51) | SLC6A4GFERHSD17B10HTR2ATRPM8 | |
| SCHEMBL6949448 | 0.82 | SLC6A4 (0.54) | SLC6A4HTR2AMEN1KMT2ALMNA | |
| SCHEMBL3702253 | 0.81 | MPO (0.62) | SLC6A4HTR2ATRPM8 | |
| SCHEMBL27500639 | 0.81 | SLC6A4 (0.52) | SLC6A4HTR2AMEN1KMT2ALMNA | |
| SCHEMBL9215791 | 0.80 | SLC6A4 (0.52) | SLC6A4GFERHSD17B10HTR2ATRPM8 | |
| SCHEMBL5203147 | 0.80 | GPR84 (0.57) | HSD17B10GPR84MTNR1AMEN1KMT2A | |
| SCHEMBL7466733 | 0.78 | SLC6A4 (0.69) | SLC6A4GFERHSD17B10HTR2ATRPM8 | |
| SCHEMBL9371057 | 0.78 | SPR (0.59) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL4362228 | 0.78 | SLC6A4 (0.61) | SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6333339-B1 | CENTRAL SYSTEM DISORDERS, SCHIZOPHRENIA AND COGNITION ACTIVATORS | MERCK PATENT GELLSCHAFT MIT BESCHRANKTER (DE) | 2001-12-25 | — | — | US | disclosed |
| CN-1260791-A | 3-benzylpiperidine | MERCK PATENT GMBH (DE) | 2000-07-19 | — | — | CN | disclosed |
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |