SCHEMBL29356264

SCHEMBL29356264

Fc1ccc(CCNC(=S)Nc2nccs2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.63
SMN1; SMN2 Q16637 6/20 0.63
ALDH1A1 P00352 6/20 0.63
NPC1 O15118 6/20 0.63
RAB9A P51151 6/20 0.63
HTT P42858 4/20 0.63
NFKB1 P19838 2/20 0.63
AGTR1 P30556 1/20 0.63
NFKB2 Q00653 1/20 0.63
RELA Q04206 1/20 0.63
L3MBTL1 Q9Y468 2/20 0.54
MAPT P10636 6/20 0.53
LMNA P02545 2/20 0.53
ALOX12 P18054 1/20 0.53
KMT2A Q03164 8/20 0.51
MEN1 O00255 5/20 0.50
PKM P14618 2/20 0.50
TP53 P04637 3/20 0.49
PLA2G1B P04054 1/20 0.49
ATG4B Q9Y4P1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280318 0.88 SMN1; SMN2 (0.55) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL6284717 0.87 KDM4E (0.57) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL1520344 0.86 SMN1; SMN2 (0.71) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL6964163 0.85 ALDH1A1 (0.54) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL29355435 0.85 ALDH1A1 (0.54) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL17186221 0.84 SMN1; SMN2 (0.61) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL6958741 0.84 LMNA (0.62) GAASMN1; SMN2ALDH1A1NPC1RAB9A
Hydrochloric Acid SCHEMBL17186439 0.83 SMN1; SMN2 (0.60) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL6958155 0.81 KDM4E (0.49) GAASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL6953393 0.81 SMN1; SMN2 (0.52) GAASMN1; SMN2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343266-A Polyurethane heat-insulating material for air film reinforced concrete dome structure 烟台市顺达聚氨酯有限责任公司 2024-01-05 CN claimed
CN-113469888-B Method and device for correcting inclination angle of circular electronic seal 江西金格科技有限公司 2023-05-05 CN claimed
EP-4635569-A2 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM Peptron, Inc. (KR) 2025-10-22 EP disclosed
US-20250295587-A1 COMPLEX LIPID NANOPARTICLES ENCAPSULATING POLYPEPTIDES AND USES THEREOF SAIL BIOMEDICINES, INC. 2025-09-25 US disclosed
US-20240398884-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2024-12-05 US disclosed
US-20240252594-A1 COMBINATION THERAPY FOR NEURODEGENERATIVE DISEASES ALETA NEUROSCIENCE LLC (US) 2024-08-01 US disclosed
US-20240210846-A1 IMAGE FORMATION APPARATUS OKI ELECTRIC INDUSTRY CO., LTD. (JP) 2024-06-27 US disclosed
US-20240058288-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY ALETA NEUROSCIENCE LLC (US) 2024-02-22 US disclosed
CN-117343266-A Polyurethane heat-insulating material for air film reinforced concrete dome structure 烟台市顺达聚氨酯有限责任公司 2024-01-05 CN disclosed
US-20240002258-A1 WATER RECLAMATION SYSTEM USING OIL AS A HEAT TRANSFER MEDIUM AND LIQUID SALT COLLECTOR Anderson Erik Andrew (US) 2024-01-04 US disclosed
US-11771657-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-03 US disclosed
WO-2023042178-A2 COMBINATION THERAPY FOR NEURODEGENERATIVE DISEASES ALETA NEUROSCIENCE, LLC (US) 2023-03-23 WO disclosed
WO-2022224118-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY ALETA NEUROSCIENCE, LLC (US) 2022-10-27 WO disclosed
US-20220288150-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-09-15 US disclosed
CN-110016479-B Alfalfa MsGPF gene 河南省农业科学院畜牧兽医研究所 2022-08-26 CN disclosed
US-20220265563-A1 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM PEPTRON, INC. (KR) 2022-08-25 US disclosed
CN-112280001-B High-flame-retardant combined polyether for floor 绍兴市华创聚氨酯有限公司 2022-06-14 CN disclosed
US-20220152139-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-05-19 US disclosed
US-11273130-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system The United States, as represented by the Secretary Department of Health and Human Services (US) 2022-03-15 US disclosed
US-11230599-B2 Tumor mutational load MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220265563-A1 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM GLP1R, IAPP, BDNF GAA 1616/4885SMN1; SMN2 47/4885ALDH1A1 4462/4885
US-20240058288-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY BAG3, BAG2, PHB1 GAA 4/4885SMN1; SMN2 751/4885ALDH1A1 1513/4885
US-11273130-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system GLP1R, IAPP, BDNF GAA 1616/4885SMN1; SMN2 47/4885ALDH1A1 4462/4885
US-11771657-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system GLP1R, IAPP, BDNF GAA 1616/4885SMN1; SMN2 47/4885ALDH1A1 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.