Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824925 | 0.77 | GAA (0.38) | MEN1KMT2A | |
| SCHEMBL6958945 | 0.72 | CRHBP (0.42) | CRHBPCRHR2MEN1KMT2AIP6K1 | |
| SCHEMBL8824956 | 0.71 | MEN1 (0.33) | MCHR1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL8825047 | 0.71 | GSK3A (0.48) | MEN1KMT2AITKIP6K1PRMT5 | |
| SCHEMBL6958317 | 0.70 | CRHBP (0.40) | CRHBPCRHR2MEN1KMT2AITK | |
| SCHEMBL6956099 | 0.69 | PPARG (0.52) | MEN1KMT2A | |
| SCHEMBL6956100 | 0.69 | PPARG (0.52) | MEN1KMT2A | |
| SCHEMBL6960807 | 0.68 | HPGDS (0.48) | CRHBPCRHR2KDM4EALDH1A1 | |
| SCHEMBL6964865 | 0.67 | PPARG (0.49) | ALDH1A1 | |
| SCHEMBL5987026 | 0.66 | ALDH1A1 (0.45) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |