Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959586 | 0.85 | HDAC1 (0.49) | HDAC1HDAC6P2RX4XIAP | |
| SCHEMBL7140109 | 0.79 | L3MBTL1 (0.45) | L3MBTL1BCHEP2RX4HPGDHTR1A | |
| SCHEMBL6972375 | 0.78 | KDM4E (0.43) | L3MBTL1BCHEP2RX4HPGDHTR1A | |
| SCHEMBL6955643 | 0.77 | L3MBTL1 (0.46) | L3MBTL1HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL6969043 | 0.77 | DRD3 (0.47) | L3MBTL1BCHEP2RX4HPGDHTR1A | |
| SCHEMBL6964416 | 0.74 | DRD2 (0.50) | L3MBTL1HPGDHTR1ATDP1ALDH1A1 | |
| SCHEMBL6959609 | 0.74 | AVPR2 (0.50) | — | |
| SCHEMBL6972297 | 0.72 | ALDH1A1 (0.46) | L3MBTL1TDP1ALDH1A1MAPTLMNA | |
| SCHEMBL8421386 | 0.71 | CES1 (0.53) | BCHEHPGDTDP1ALDH1A1ATM | |
| SCHEMBL6960672 | 0.71 | L3MBTL1 (0.46) | L3MBTL1TDP1ALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |