Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161783 | 0.76 | HTR6 (0.61) | MAPTHTR6TSHRCTSGCMA1 | |
| SCHEMBL6958683 | 0.75 | PTGS2 (0.39) | MAPTALDH1A1CYP19A1CA12CA1 | |
| SCHEMBL4638794 | 0.70 | HSD11B1 (0.44) | MAPTHTR6TSHRALDH1A1MEN1 | |
| SCHEMBL6966187 | 0.69 | AGTR1 (0.51) | MAPTHTR6ALDH1A1MEN1KMT2A | |
| SCHEMBL315684 | 0.69 | HTR6 (0.54) | HTR6TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27910606 | 0.68 | HTR6 (0.54) | MAPTHTR6TSHRCTSGCMA1 | |
| SCHEMBL7672297 | 0.68 | HTR6 (0.48) | MAPTHTR6TSHRALDH1A1KMT2A | |
| SCHEMBL8514633 | 0.67 | CA2 (0.59) | MAPTHTR6TSHRALDH1A1CYP3A4 | |
| (Phenylsulfonyl)Benzene SCHEMBL1549229 | 0.66 | HTR6 (0.93) | MAPTHTR6TSHRALDH1A1SMN1; SMN2 | |
| (Phenylsulfonyl)Benzene SCHEMBL5537560 | 0.66 | HTR6 (0.93) | MAPTHTR6TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |